This study analyzed factors affecting the occurrence of occupational injuries in the logistics industry, focusing on the delivery service, in particular. In this study, workers who are prone to occupational injuries in the delivery service were divided into those who sort packages in the distribution centers and couriers. In order to analyze factors affecting the occurrence of occupational injuries in distribution center workers, a factor analysis was performed to derive five independent variables, including workplace safety management, conveyor safety management, workload of distribution center, forklift safety management, and the management of employee breaks, and a dependent variable of the number of victims. The analysis found that among the five independent variables, workload of distribution centers and conveyor safety management had an effect on the dependent variable. On the other hand, workplace safety management, forklift safety management, and the management of employee breaks had no significant effect on the occurrence of incidents. To analyze factors affecting the occurrence of occupational injuries in couriers, work hours, time for sorting packages, delivery hours, delivery quantity, number of night shifts, first delivery time, average daily driving distance, rest periods, and shipment volume and weight were used as independent variables. For dependent variables, physical burden, occurrence of health problems, and the experience of occupational incidents were used. As a result of analyzing the factors affecting physical burden, the total work hours, delivery quantity, time spent for first delivery, number of night shifts per week during the peak season, rest periods, and shipment volume and weight were found to affect physical burden. On the other hand, time for sorting packages, delivery hours, number of night shifts during the off season, and average daily driving distance did not show any effect on physical burden. The most important factors affecting health problems were increase in the total work hours during the peak season and the extreme extension of hours spent for sorting and shipping, which affect the total work hours. In addition, increase in the average daily driving distance and shipment volume and weight also affected health problems. Occupational incidents showed somewhat similar results as health problems; long total work hours and delivery hours showed an effect on the experience of occupational incidents. Although shipment volume and weight affected occupational incidents, delivery work or average daily driving distance did not show any effect.